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Product Name TRITC-labelled Hyaluronic Acid, >1000 Kda
Synonyms HA, Hyaluronan, Hyaluronate, Sodium hyaluronate, Poly(b-glucuronic acid-[1→3]-b-N-acetylglucosamine-[1→4]); α-ΔUA-(1→27)-GlcNAc; sodium hyaluronate powder, hyaluronic acid; hyalobarrier gel; haluronic acid; hyaluronic acid sodium; hyaluronic acid na-salt;
Morphology & Appearance White powder
Molecular Weight G/Mol >1000 Kda
Storage The dried product should be stored in air-tight containers at ambient temperatures in the dark. A shelf-life of 5 years is proposed. No release of fluorescent material was noted when a solution of the product was incubated at pH 7.5 at 37°C for one month.
Application Tetramethyl-rhodamine hyaluronic acid (TR-HA) has similar applications to those described for fluorescein hyaluronic acid but has certain advantages. As mentioned earlier, the fluorescence of tetramethylrhodamine is less dependent on pH than FITC-labels. Also the longer emission wavelength avoids interference from background images in experimental environments. Invasive growth into brain tissue employing TR-HA and 2-photon imaging has been described.